Micropolar Fluid Model for Blood Flow Through Catheterized Arteries: Understanding Stenosis and Thrombosis

About Course

This course delves into the complex dynamics of blood flow through arteries, specifically focusing on catheterized arteries with stenosis and thrombosis. Using the micropolar fluid model, students will learn how blood’s rheological properties are influenced by stenotic and thrombotic conditions. The study also covers non-isothermal blood flow, emphasizing the impact of various physical parameters like velocity, temperature, shear stress, and resistance. The course uses mathematical formulations and validated numerical methods to explore these critical biological phenomena in biomedical engineering.

Students will also explore the innovative coupling of micropolar fluid mechanics with real-life medical applications, providing insights into improving medical devices like catheters. The course is designed for students interested in computational fluid dynamics (CFD), bioengineering, and medical physics, offering practical knowledge for solving challenging health problems related to blood flow in arteries.

Abstract:

This paper presents a comprehensive analysis of non-isothermal blood flow through a catheterized artery, taking into account stenosis and thrombosis. By utilizing the micropolar fluid model, the authors develop equations to describe blood flow and heat transfer in arteries. The model captures essential fluid characteristics, such as microrotation, that influence blood movement in constrained conditions. The study’s primary aim is to understand how these factors impact shear stress, wall resistance, and overall blood flow within arteries, particularly under disease conditions. The paper also explores the temperature and velocity profiles of blood, validated with the BVP4C approach, and offers detailed insights into the resistance to blood flow caused by blockages in the artery.

DOI: 

Application of micropolar fluid model to blood flow through catheterized artery with stenosis and thrombosis

Cite: 

 

 

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What Will You Learn?

  • Understand the principles of the micropolar fluid model and its application to blood flow in arteries.
  • Learn how stenosis and thrombosis affect blood flow in catheterized arteries.
  • Analyze the governing equations for blood flow and heat transfer in arterial systems.
  • Apply computational fluid dynamics (CFD) techniques to simulate blood flow under diseased conditions.
  • Study the impact of various physical parameters, including velocity, temperature, shear stress, and wall resistance, on blood flow.
  • Gain experience in numerical methods such as the BVP4C approach for solving flow-related equations.
  • Explore real-world applications in biomedical engineering, particularly in the design of medical devices like catheters.
  • Understand the significance of microrotation and non-isothermal effects in biological systems.

Course Content

Module 1: Introduction to Micropolar Fluid Model
Understanding the basics of micropolar fluids The significance of microrotation effects in blood flow Introduction to the physical properties of blood in different flow conditions

Module 2: Stenosis and Thrombosis in Arteries
What are stenosis and thrombosis? How these conditions impact blood flow Case studies and medical relevance

Module 3: Mathematical Formulation of Micropolar Fluid Model
Governing equations of blood flow in arteries Application of the model in stenotic and thrombotic conditions Boundary conditions and numerical solutions for velocity and pressure profiles

Module 4: Non-Isothermal Blood Flow
Temperature distribution and heat transfer in arteries Impact of temperature gradients on blood flow Theoretical solutions and experimental data comparison

Module 5: Numerical Solutions and Validation
BVP4C method for solving governing equations Numerical techniques for simulating blood flow Comparison with experimental data for validation

Module 6: Impact of Physical Parameters on Blood Flow
Effect of heat source, clot height, and stenosis dimensions Understanding the velocity and shear stress profiles Impact of coupling number and micropolar parameters

Module 7: Applications of Micropolar Fluid Model in Biomedical Engineering
Medical devices influenced by blood flow dynamics Design considerations for catheters and other surgical tools Future research directions and innovative solutions in the field

Module 8: Practical Case Studies
Simulating real-life blood flow scenarios Analysis of different artery models with various degrees of stenosis and thrombosis Solutions for optimizing blood flow in diseased arteries

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